Formation of a 3,4-diol-1,2-epoxide metabolite of benz[a]anthracene with cytotoxicity and genotoxicity in a human in vitro hepatocyte culture system
Keywords: BA, benz[a]anthracene; BA-3,4-diol-1,2-epoxide, benz[a]anthracene-3,4-diol-1,2-epoxide; CYP, cytochrome P450; AKR, aldo-keto reductase; ROS, reactive oxygen species; B[a]P, benzo[a]pyreneBenz[a]anthracene; Cytochrome P450; Aldo-keto reductase; Benz[a]anth